Translational regulation in mammalian cells.
نویسندگان
چکیده
منابع مشابه
Synergetic regulation of translational reading-frame switch by ligand-responsive RNAs in mammalian cells
Distinct translational initiation mechanisms between prokaryotes and eukaryotes limit the exploitation of prokaryotic riboswitch repertoire for regulatory RNA circuit construction in mammalian application. Here, we explored programmed ribosomal frameshifting (PRF) as the regulatory gene expression platform for engineered ligand-responsive RNA devices in higher eukaryotes. Regulation was enabled...
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BRCA1 (Breast Cancer 1) has been implicated in a number of cellular processes, including transcription regulation, DNA damage repair and protein ubiquitination. We previously demonstrated that BRCA1 interacts with PABP1 (Poly(A)-Binding Protein 1) and that BRCA1 modulates protein synthesis through this interaction. To identify the mRNAs that are translationally regulated by BRCA1, we used a mic...
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ژورنال
عنوان ژورنال: Journal of the agricultural chemical society of Japan
سال: 1990
ISSN: 0002-1407,1883-6844
DOI: 10.1271/nogeikagaku1924.64.927